Triple negative breast cancer studies

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Article Summary. If you have Triple Negative Breast Cancer (TNBC) or are concerned about it, there are a lot of natural ways to treat it that do not involve surgery, chemotherapy, and/or radiation.

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This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer.


In all cases where the tumor is classified as triple-negative, treatment options become a bit more limited than with other subtypes of breast cancer. Results from a phase Ib trial suggest that the programmed death 1 (PD-1) inhibitor pembrolizumab has activity and an acceptable toxicity profile as single-agent therapy in heavily pretreated, advanced triple-negative breast cancer (TNBC).
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The purpose of this study is to compare the safety and efficacy of nab-paclitaxel in combination with either gemcitabine or carboplatin to the combination of gemcitabine and carboplatin as first line treatment in female subjects with triple negative metastatic breast cancer (TNMBC) or metastatic triple negative breast cancer.

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Breast cancer is the most common noncutaneous cancer in U.S. women, with an estimated 63, cases of in situ disease and , cases of invasive disease in [] Thus, fewer than one of six women diagnosed with breast cancer die of the disease. Breast cancer is a heterogeneous disease, and within the HER-2 positive subtype this is highly exemplified by the presence of substantial phenotypical and clinical heterogeneity, mostly related to hormonal receptor (HR) expression.

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SAN ANTONIO — Patients with stage 2 or stage 3 triple-negative breast cancer (TNBC) who had a pathologic complete response (pCR) after presurgery chemotherapy had increased event-free and overall survival compared with those who had more than minimal residual . Breast cancer will affect 1 in 8 women during their lifetime — and it is the fourth-leading cause of cancer death in the United States. But 8 in 8 women are being exploited by those looking to .

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Breast cancer is responsible for more than 40, deaths in the United States each year, along with more than , cancer diagnoses. Fortunately, new treatments have pushed the disease's five-year survival rate to nearly 90%. Breast cancer is responsible for more than 40, deaths in the United. Abstract. Breast cancer cell lines have been widely used for breast cancer modelling which encompasses a panel of diseases with distinct phenotypical associations.
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Breast cancer ranks as one of the leading cancer types in the number of new cases diagnosed and is second only to lung cancer as the the most prevalent cause of cancer death in women. May 22, · Get information on breast cancer awareness, signs, symptoms, stages, types, treatment, and survival rates. Around 40, women in the U.S. die of breast cancer each year. Read about prevention and early symptoms.

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